Description
MK-677 Ibutamoren liquid from Blue Sky Peptide is a 30mL glass dropper bottle of MK-677 (ibutamoren) at 25mg/mL, 750mg in total. MK-677 is an orally active nonpeptide growth hormone secretagogue. This batch tested at 99.65% purity. It’s sold for laboratory research only.
About MK-677 (ibutamoren)
MK-677 (ibutamoren) is an orally active, nonpeptide growth hormone secretagogue developed by Merck. It mimics ghrelin at the GHS-R1a receptor, raising growth hormone and IGF-1. It’s often sold next to SARMs, but it isn’t one.
It was never approved as a medicine, and it’s on the WADA prohibited list.
How MK-677 works
MK-677 binds GHS-R1a, the same receptor as ghrelin and the GHRP peptides, in the pituitary and hypothalamus. That boosts the size of natural GH pulses and lifts IGF-1 from the liver.
Because it’s a small molecule, not a peptide, it survives digestion and lasts about a day, which is what made it attractive as an oral research tool. The same receptor drives hunger, so appetite goes up too.
MK-677 Ibutamoren liquid technical data
- Compound: MK-677 (ibutamoren)
- CAS number: 159634-47-6
- Molecular formula: C27H36N4O5S
- Molar mass: 528.7 g/mol
- Structure: spiro-piperidine small molecule (supplied as the mesylate salt)
- Concentration: 25mg/mL
- Volume: 30mL (750mg in total)
- Form: ready-made liquid in a glass dropper bottle
- Purity: 99.65% (mass spectrometry and HPLC-UV)
- SKU: BSP-MK677-30
- Use: laboratory research only
MK-677 research
Nass and colleagues ran a two-year trial in healthy older adults, published in the Annals of Internal Medicine in 2008. MK-677 raised GH and IGF-1 to levels seen in young adults and increased fat-free mass, with rises in fasting glucose noted.
Earlier Merck studies by Chapman and colleagues described how it raises GH while keeping the normal pulse pattern.
The primary literature is on PubMed. Here’s a search for MK-677 studies to start from.
MK-677 Ibutamoren liquid vs related compounds
Here’s how MK-677 Ibutamoren liquid fits among related compounds. MK-677 is an oral ghrelin mimic that raises GH and IGF-1, not a SARM. By comparison:
- MK-2866 is the most studied SARM, with a phase 2 trial in cancer-related muscle loss
- LGD-4033 binds the androgen receptor very tightly and has a published phase 1 study
- RAD-140 showed strong muscle selectivity in monkeys and was trialed in breast cancer
- S4 Andarine is a partial androgen receptor agonist, one of the first SARMs from GTx
- YK-11 is a steroidal partial agonist that raises follistatin in muscle cells
- GW501516 is a PPAR-delta agonist that shifts muscle toward burning fat, not a SARM
Only the first five act on the androgen receptor. MK-677 and GW501516 are sold alongside SARMs because they’re studied for body composition too, but they work through different receptors. See them all on our SARMs page.
Measuring MK-677 Ibutamoren liquid
The concentration is 25mg/mL, so the math is simple: every 1mL holds 25mg, and every 0.1mL holds 2.5mg. The whole 30mL bottle holds 750mg.
For accurate volumes, draw with a graduated 1mL measuring dropper instead of the cap dropper. It’s marked in 0.1mL steps, so you can measure to the nearest tenth of a milliliter.
Storing MK-677 Ibutamoren liquid
Room temperature is fine for MK-677 Ibutamoren liquid. Keep it upright, capped and out of the sun, and write the opening date on the label.
MK-677 Ibutamoren liquid purity and testing
Purity for this batch of MK-677 Ibutamoren liquid came back at 99.65% by HPLC and mass spectrometry. That’s the figure for the batch currently in stock.
The label on each bottle shows the compound, the strength and the batch. Ask us for the certificate of analysis for your batch and we’ll email it over.
Keep the batch number with your records. It’s the quickest way to match a bottle to its paperwork later.
Compounds often ordered with MK-677
- MK-2866 Ostarine Liquid 35mg/mL (30mL), a SARM in a 30mL bottle
- LGD-4033 Liquid 10mg/mL (30mL), a SARM in a 30mL bottle
- S4 Andarine Liquid 25mg/mL (30mL), a SARM in a 30mL bottle
- RAD-140 Liquid 10mg/mL (30mL), a SARM in a 30mL bottle
- GW501516 Cardarine Liquid 10mg/mL (30mL), a PPAR-delta agonist in a 30mL bottle
Browse the full SARMs range, or see everything on our research liquids page.
MK-677 Ibutamoren liquid questions
How much is in the MK-677 Ibutamoren liquid bottle?
30mL of solution at 25mg/mL, which is 750mg in total. The amount is printed on the label.
Can MK-677 be used in people or animals?
No. It’s sold for laboratory research only and isn’t approved for human or veterinary use.
Is MK-677 Ibutamoren liquid in stock?
Yes, MK-677 Ibutamoren liquid is in stock now and ready to ship.
Is there a COA for MK-677 Ibutamoren liquid?
Yes. Each batch has a certificate of analysis filed under the batch number on the label. Email us that number and we’ll send it.
Does MK-677 Ibutamoren liquid need mixing?
No. It’s already a solution in a dropper bottle, so there’s no powder to reconstitute.
Buy MK-677 Ibutamoren liquid online
Order MK-677 Ibutamoren liquid now for $74.07. It’s in stock, and checkout takes about two minutes.
Need more for the same project? See the rest of our SARMs.
For laboratory research use only. Not for human or veterinary use. Not evaluated by the FDA.






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