MGF (Mechano Growth Factor) 2mg

Description

MGF 2mg from Blue Sky Peptide is 2mg of MGF in a sealed glass vial. MGF is an IGF-1 splice variant peptide. This batch tested at 99.09% purity. It’s for in-vitro and lab research only.

MGF at a glance

Mechano growth factor is a version of IGF-1 that muscle makes after mechanical load or damage. It comes from alternative splicing of the IGF-1 gene and is called IGF-1Ec in humans. The research peptide is a synthetic copy of its unique E-domain tail, 24 amino acids long.

Geoffrey Goldspink’s group at the Royal Free Hospital in London described it in the 1990s and gave it the name.

How MGF works

When muscle is stretched or damaged, the IGF-1 gene is spliced differently and makes MGF first, before the main IGF-1 form. The idea is that MGF’s E-domain wakes up satellite cells, the muscle stem cells that repair fibers.

The synthetic E-peptide has no IGF-1 receptor binding domain, so any effect it has is meant to come through a different, still unidentified route. Free MGF peptide also breaks down within minutes, which is why a pegylated version exists.

MGF 2mg product details

• Compound: MGF
• Also known as: mechano growth factor, IGF-1Ec E-peptide
• Molecular formula: C121H200N42O39
• Sequence: Tyr-Gln-Pro-Pro-Ser-Thr-Asn-Lys-Asn-Thr-Lys-Ser-Gln-Arg-Arg-Lys-Gly-Ser-Thr-Phe-Glu-Glu-His-Lys
• Amount: 2mg per vial
• Form: lyophilized (freeze-dried) white powder
• Source: chemical synthesis
• Purity: 99.09% (mass spectrometry and HPLC-UV)
• SKU: BSP-MGF-2
• Use: laboratory research only

What the research says about MGF

Yang and Goldspink reported in FEBS Letters in 2002 that the MGF E-peptide made muscle satellite cells divide more, separately from the main IGF-1 receptor.

Later studies looked at it in heart and nerve injury models. Some groups couldn’t reproduce every result, so the field still argues about how much of it acts on its own. All of the work is in cells and animals.

The primary literature is on PubMed. Here’s a search for MGF studies to start from.

How MGF compares

MGF 2mg is easier to place once you see it next to the compounds it’s usually compared with. MGF is the E-domain peptide from the muscle-specific IGF-1 splice variant. The others:

• IGF-1 LR3 is an 83-amino-acid IGF-1 analog that avoids binding proteins and lasts for hours
• IGF-1 DES is IGF-1 missing three residues, potent locally but cleared faster than IGF-1 LR3
• PEG-MGF is MGF with a PEG chain added so it lasts much longer

These sit downstream of growth hormone, on the IGF-1 side of the axis. They differ in how they avoid binding proteins, how long they last and which receptor they rely on. See them all on our growth hormone peptides page.

Lab-tested MGF 2mg

Purity for this batch of MGF 2mg came back at 99.09% by HPLC and mass spectrometry. That’s the figure for the batch currently in stock.

Note the batch number on the label when the vial arrives. That’s what the certificate of analysis is filed under, and we’ll send you a copy on request.

Keep the batch number with your records. It’s the quickest way to match a vial to its paperwork later.

Reconstituting MGF 2mg

Here’s the math for 2mg of peptide:

• 1mL of water gives 2mg/mL
• 2mL of water gives 1mg/mL

Choose the volume that suits your measurements. Mark the vial with the concentration and date so nobody has to guess later.

Use sterile bacteriostatic water. Warm the sealed vial to room temperature first so no condensation gets in, add the water slowly along the glass wall, and swirl gently until it’s clear. Never shake it.

How to store MGF 2mg

The dry powder keeps best cold. A freezer at -20°C is ideal for long-term storage, and a fridge works for a few weeks. After reconstitution, store it in the fridge and finish it within roughly four weeks.

A 10-slot vial case keeps open and sealed vials upright and apart, which makes the fridge shelf a lot easier to manage. For transport, the Blue Sky hard storage box is the sturdier option.

MGF 2mg quantity deals

You can buy MGF 2mg one vial at a time, take the free-vial deal or order in bulk. The options in the dropdown are:

• 1 vial: $35.72
• Buy 1 get 1 free: 2 vials for $35.72
• Bulk 50 pack: 50 vials for $747.50, about $14.95 a vial
• Bulk 100 pack: 100 vials for $1,395.00, about $13.95 a vial
• Bulk 200 pack: 200 vials for $2,590.00, about $12.95 a vial

The free-vial offer is the easiest saving if you’ll use more than one vial. The free vial is the same product from the same stock.

Bulk packs are meant for labs and resellers running larger studies. Every vial is sealed separately, so you only open what you need and keep the rest in storage. See all our bulk peptides for other compounds sold this way.

Related to MGF 2mg

• HGH Fragment 176-191 5mg, an hGH fragment
• GHRP-2 5mg, a GH releasing peptide
• Ipamorelin 2mg, a GH secretagogue
• Sermorelin 2mg, a GHRH analog
• GHRP-6 5mg, a GH releasing peptide

Browse the full growth hormone peptides and healing and recovery peptides range, or see everything on our research peptides page.

Common questions about MGF 2mg

How much is in the MGF 2mg vial?

2mg of freeze-dried powder. The amount is printed on the label.

Can MGF be used in people or animals?

No. It’s sold for laboratory research only and isn’t approved for human or veterinary use.

Is MGF 2mg in stock?

Yes, MGF 2mg is in stock now and ready to ship.

Is there a COA for MGF 2mg?

Yes. Each batch has a certificate of analysis filed under the batch number on the label. Email us that number and we’ll send it.

Is there a deal for buying more than one?

Yes. Choose Buy 1 Get 1 Free to get two vials for the price shown in the dropdown.

Order MGF 2mg today

Order MGF 2mg now for $35.72. It’s in stock, and checkout takes about two minutes.

Need more for the same project? See the rest of our growth hormone peptides and healing and recovery peptides.

For laboratory research use only. Not for human or veterinary use. Not evaluated by the FDA.