Retatrutide 10mg (Reta)

Description

Retatrutide 10mg is a 10mg vial of Retatrutide (sold as Reta), a GIP, GLP-1 and glucagon receptor agonist, supplied by Blue Sky Peptide as freeze-dried powder. This batch tested at 99.66% purity. It’s for in-vitro and lab research only.

What is Retatrutide?

Retatrutide (LY3437943, often sold as GLP-3R) is a single peptide from Eli Lilly that acts on three receptors: GIP, GLP-1 and glucagon.

It’s still in clinical trials.

How Retatrutide acts in the lab

Retatrutide hits three receptors with one peptide: GIP, GLP-1 and glucagon. The first two are incretins that boost glucose-dependent insulin release and, in GLP-1’s case, curb appetite and slow stomach emptying.

The glucagon part is the unusual bit. Glucagon raises energy expenditure and pushes the liver to burn fat, so pairing it with the incretins is meant to work on both sides of energy balance. That’s the main reason researchers compare it with the dual and single agonists.

Retatrutide 10mg technical data

• Compound: Retatrutide
• Also known as: LY3437943
• CAS number: 2381089-83-2
• Molar mass: 4,731.3 g/mol
• Structure: 39 amino acids with a fatty diacid side chain
• Amount: 10mg per vial
• Form: lyophilized (freeze-dried) white powder
• Source: chemical synthesis
• Purity: 99.66% (mass spectrometry and HPLC-UV)
• SKU: BSP-RETA-10
• Use: laboratory research only

What the research says about Retatrutide

Jastreboff and colleagues reported in the New England Journal of Medicine (2023) a mean weight loss of up to 24% at 48 weeks in a phase 2 trial.

Phase 3 trials are under way.

To read the papers yourself, start with this PubMed search for Retatrutide.

How Retatrutide compares

Here’s how Retatrutide 10mg fits among related compounds. Retatrutide hits GLP-1, GIP and glucagon receptors, the triple agonist with the biggest phase 2 numbers so far. By comparison:

• Semaglutide acts on the GLP-1 receptor only and lasts about a week, the most studied compound in the group
• Tirzepatide adds GIP receptor activity to GLP-1, a dual agonist with larger weight effects than semaglutide in trials
• Cagrilintide works through amylin receptors instead of incretins, often studied next to or with semaglutide

The main difference between these compounds is which receptors they hit. Pick the one that matches the receptor question in your study, and use the others as comparisons. See them all on our GLP-1 peptides page.

Lab-tested Retatrutide 10mg

The current batch of Retatrutide 10mg tested at 99.66% purity by mass spectrometry and UV (HPLC) analysis. That figure comes from the batch report, not a marketing estimate, and it’s the reason we list the exact number instead of rounding up.

The label on each vial shows the compound, the strength and the batch. Ask us for the certificate of analysis for your batch and we’ll email it over.

If a result looks off, check the batch number first, then your handling notes. Most problems with Retatrutide come from storage or mixing, not the material.

Reconstituting Retatrutide 10mg

Concentration is the amount in the vial divided by the liquid you add. With 10mg in this vial:

• 1mL of water gives 10mg/mL
• 2mL of water gives 5mg/mL
• 3mL of water gives 3.33mg/mL

Pick the volume that keeps your own calculations simple, then write the concentration and the mixing date on the label.

Use sterile bacteriostatic water. Warm the sealed vial to room temperature first so no condensation gets in, add the water slowly along the glass wall, and swirl gently until it’s clear. Never shake it.

How to store Retatrutide 10mg

The dry powder keeps best cold. A freezer at -20°C is ideal for long-term storage, and a fridge works for a few weeks. After reconstitution, store it in the fridge and finish it within roughly four weeks.

If you keep several vials going at once, our vial storage case holds ten upright with room for labels, and the hard storage box protects them in a shared freezer or in transit.

Choosing a Retatrutide strength

• Retatrutide 10mg (Reta) (this page): 10mg for $129.97, about $13.00 per mg
• Retatrutide 20mg (Reta): 20mg for $194.99, about $9.75 per mg

Retatrutide 10mg is the smaller option. It’s the one to start with for a pilot run or when you’re testing a new protocol.

Compounds often ordered with Retatrutide

• Cagrilintide 5mg, an amylin analog
• CagriSema Blend 5mg/5mg, Cagrilintide and Semaglutide in one vial
• Semaglutide 5mg, a GLP-1 agonist
• Tirzepatide 10mg (Tirz), a GIP/GLP-1 agonist
• 5-Amino-1MQ 10mg, an NNMT inhibitor

Browse the full GLP-1 peptides and weight loss peptides range, or see everything on our research peptides page.

Retatrutide 10mg questions

How much is in the Retatrutide 10mg vial?

10mg of freeze-dried powder. The amount is printed on the label.

Is Retatrutide 10mg in stock?

Yes, Retatrutide 10mg is in stock now and ready to ship.

Is Reta the same as retatrutide?

Yes. Reta is the short name on our label, and the vial holds retatrutide.

Is there a COA for Retatrutide 10mg?

Yes. Each batch has a certificate of analysis filed under the batch number on the label. Email us that number and we’ll send it.

What do I mix Retatrutide 10mg with?

Sterile bacteriostatic water is the usual choice. The reconstitution section above shows the concentration for each volume.

Buy Retatrutide 10mg online

Ready to order? Retatrutide 10mg costs $129.97 and is in stock. Add it to your cart and you’re done. Ordering several vials? Add a storage case to keep them together.

Need more for the same project? See the rest of our GLP-1 peptides and weight loss peptides.

For laboratory research use only. Not for human or veterinary use. Not evaluated by the FDA.