Retatrutide 20mg (Reta)

Description

Our Retatrutide 20mg vial holds 20mg of lyophilized Retatrutide (sold as Reta), a GIP, GLP-1 and glucagon receptor agonist. This batch tested at 99.66% purity. It’s for in-vitro and lab research only.

About Retatrutide

Retatrutide (LY3437943, often sold as GLP-3R) is a single peptide from Eli Lilly that acts on three receptors: GIP, GLP-1 and glucagon.

It’s still in clinical trials.

Retatrutide mechanism of action

Retatrutide hits three receptors with one peptide: GIP, GLP-1 and glucagon. The first two are incretins that boost glucose-dependent insulin release and, in GLP-1’s case, curb appetite and slow stomach emptying.

The glucagon part is the unusual bit. Glucagon raises energy expenditure and pushes the liver to burn fat, so pairing it with the incretins is meant to work on both sides of energy balance. That’s the main reason researchers compare it with the dual and single agonists.

Retatrutide 20mg product details

• Compound: Retatrutide
• Also known as: LY3437943
• CAS number: 2381089-83-2
• Molar mass: 4,731.3 g/mol
• Structure: 39 amino acids with a fatty diacid side chain
• Amount: 20mg per vial
• Form: lyophilized (freeze-dried) white powder
• Source: chemical synthesis
• Purity: 99.66% (mass spectrometry and HPLC-UV)
• SKU: BSP-RETA-20
• Use: laboratory research only

Published Retatrutide studies

Jastreboff and colleagues reported in the New England Journal of Medicine (2023) a mean weight loss of up to 24% at 48 weeks in a phase 2 trial.

Phase 3 trials are under way.

For the original studies, try this PubMed search.

Retatrutide 20mg vs related compounds

Here’s how Retatrutide 20mg fits among related compounds. Retatrutide hits GLP-1, GIP and glucagon receptors, the triple agonist with the biggest phase 2 numbers so far. By comparison:

• Semaglutide acts on the GLP-1 receptor only and lasts about a week, the most studied compound in the group
• Tirzepatide adds GIP receptor activity to GLP-1, a dual agonist with larger weight effects than semaglutide in trials
• Cagrilintide works through amylin receptors instead of incretins, often studied next to or with semaglutide

The main difference between these compounds is which receptors they hit. Pick the one that matches the receptor question in your study, and use the others as comparisons. See them all on our GLP-1 peptides page.

Retatrutide 20mg purity and testing

The current batch of Retatrutide 20mg tested at 99.66% purity by mass spectrometry and UV (HPLC) analysis. That figure comes from the batch report, not a marketing estimate, and it’s the reason we list the exact number instead of rounding up.

The label on each vial shows the compound, the strength and the batch. Ask us for the certificate of analysis for your batch and we’ll email it over.

If a result looks off, check the batch number first, then your handling notes. Most problems with Retatrutide come from storage or mixing, not the material.

Retatrutide 20mg reconstitution and concentration

Concentration is the amount in the vial divided by the liquid you add. With 20mg in this vial:

• 1mL of water gives 20mg/mL
• 2mL of water gives 10mg/mL
• 3mL of water gives 6.67mg/mL

Choose the volume that suits your measurements. Mark the vial with the concentration and date so nobody has to guess later.

Most labs use sterile bacteriostatic water. Let the vial reach room temperature, run the water slowly down the inside of the glass, then roll the vial gently until the powder dissolves. Don’t shake it. Shaking can shear peptide chains.

Retatrutide 20mg storage and shelf life

Store sealed vials of Retatrutide 20mg in the freezer (-20°C) or the fridge (2 to 8°C), out of direct light. Mixed solution goes back in the fridge and should be used within about 28 days.

If you keep several vials going at once, our vial storage case holds ten upright with room for labels, and the hard storage box protects them in a shared freezer or in transit.

Choosing a Retatrutide strength

• Retatrutide 10mg (Reta): 10mg for $129.97, about $13.00 per mg
• Retatrutide 20mg (Reta) (this page): 20mg for $194.99, about $9.75 per mg

Retatrutide 20mg is the larger size and the cheaper one per milligram. It suits longer studies where you’d otherwise reorder.

Related to Retatrutide 20mg

• CagriSema Blend 5mg/5mg, Cagrilintide and Semaglutide in one vial
• Semaglutide 5mg, a GLP-1 agonist
• Tirzepatide 10mg (Tirz), a GIP/GLP-1 agonist
• Cagrilintide 5mg, an amylin analog
• 5-Amino-1MQ 10mg, an NNMT inhibitor

Browse the full GLP-1 peptides and weight loss peptides range, or see everything on our research peptides page.

Retatrutide 20mg questions

How much is in the Retatrutide 20mg vial?

20mg of freeze-dried powder. The amount is printed on the label.

How should I store it?

Sealed vials keep at room temperature in transit. For storage, use the freezer long term or the fridge for a few weeks. Once mixed, refrigerate and use within about 28 days.

Can Retatrutide be used in people or animals?

No. It’s sold for laboratory research only and isn’t approved for human or veterinary use.

Is Retatrutide 20mg in stock?

Yes, Retatrutide 20mg is in stock now and ready to ship.

Is Reta the same as retatrutide?

Yes. Reta is the short name on our label, and the vial holds retatrutide.

Buy Retatrutide 20mg from Blue Sky Peptide

Retatrutide 20mg is in stock at $194.99. Add it to the cart and check out in a couple of minutes. Ordering several vials? Add a storage case to keep them together.

Need more for the same project? See the rest of our GLP-1 peptides and weight loss peptides.

For laboratory research use only. Not for human or veterinary use. Not evaluated by the FDA.